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Test Code AHS Abnormal Hematology Smear Path Review

Important Note

This orderable is reflexed by laboratory staff only. If a provider needs Pathology Smear Review please refer to Pathology Smear Review.

Methodology

Slides are prepared from EDTA whole blood specimens using a push prep technique to create a thin monolayer of cells which are then air-dried and stained with Modified Wright’s-Giemsa stain. The smears are examined under a microscope, using magnifications designed to adequately identify and/or count cells. All slide reviews are correlated with histogram results from the CBC analyzer, and include evaluation of WBC, RBC, and Platelet populations.

Result Reporting and Reference Values

Results are reported as free text observations/ recommendations by performing Pathologist.

Useful For

Abnormal Hematology Smear Path Review are reflexed by the laboratory on CBC specimens for:

  • Unexplained Hgb below 7 gm/dl if accompanied by abnormal RBC morphology or low or high MCV.
  • Unexplained presence of normoblasts.
  • Two (2) or more metamyelocytes or earlier precursors, including blasts, present for no obvious reason such as infection.
  • Monocytosis or Eosinophilia with other abnormalities present.
  • Any unexplained absolute deficiency of lymphocytes or granulocytes.
  • Any unexplained absolute increase of lymphocytes.
  • Any bizarre cells
  • Atypical lymphocytes greater than 20/100 WBCs or greater than 10 % if accompanied by an absolute lymphocytosis.
  • MCV greater than 110.
  • MCH less than 20 pcg or greater than 37 pcg.
  • MCHC greater than 37 gm/dL.
  • RDW greater than 22.0 %.
  • Platelet count less than 50,000 µL or greater than 1,000,000 µL (first time only).

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