Test Code hCG Quant HCG Quantitative Blood
Additional Codes
Cerner |
NextGen |
HCG Quantitative Serum |
HCG Quantitative Serum |
HCG Quantitative Blood |
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Alternate Name(s)
β-hCG
Beta Human Chorionic Gonadotropin
Quantitative Pregnancy
Useful For
The detection of hCG in urine or blood within 3-4 weeks of the last menstrual period is the most reliable indicator for the confirmation of pregnancy. β-hCG is initially secreted by the trophoblast, and later by the chorion and placenta. Levels rise exponentially to a peak during the first trimester, declining to a plateau during the second and third trimesters. Measurement of hCG has also been applied in the diagnosis of ectopic pregnancy, threatened abortion, and multiple gestation.
Methodology
Immunometric (Chemiluminescence)
Patient Preparation
None
Collection Instructions
Standard phlebotomy practices.
Specimen Requirements
Container |
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Stability |
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Rejection Criteria |
Gross Hemolysis |
Result Reporting and Reference Values
Reported in Units/L
Most Likely Not Pregnant (Negative) |
0 - 5 |
Pregnant (Positive) |
≥ 25 |
Approximate Gestational Age in weeks. |
Approximate hCG Range |
Non Pregnant female |
<5.0 |
1-10 |
64 - 150,854 |
11-15 |
11,795 - 151,996 |
16-22 |
9,384 - 61,410 |
23-40 |
1,737 - 98,576 |
Reflex Testing
None
Limitations
- Ortho reports a bias with the following:
- Biotin can cause a negative bias
- Ortho reports no significant effect with the following:
- Bilirubin up to 20 mg/dL
- Hemoglobin up to 500 mg/dL
- The following interpretive data is visible to the practitioner:
- Levels less than 25 units/L do not exclude pregnancy. A further sample should be tested after 48 hours if pregnancy is suspected