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HelpTest Code UPRO12HR Protein Urine 12 Hour
Additional Codes
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Cerner |
NextGen |
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Protein Urine 12 Hr |
Protein Urine 12 Hr |
Methodology
Colorimetric (reflectance spectrophotometry) using pyrocatechol violet dye.
Patient Preparation
None
Collection Instructions
Catheterized specimens collected according to clinical policies and procedures
24 Hour Urine Collection Instructions should be followed but adapted for 12 hours
Specimen Requirements
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Container |
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Stability |
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Rejection Criteria |
Hemolyzed or blood specimens |
Result Reporting and Reference Values
- Reported in mg/12hr
- No reference range established
Reflex Testing
None
Limitations
- Ortho reports a bias with the following:
- Hemoglobin at 50 mg/dL can cause a +30.64 mg/dL bias.
- Ceftriaxone at 550 mg/dL can cause a +119.27 mg/dL bias
- Deferoxamine mesylate at 750mg/dL can cause a +32.52 mg/dL bias
- NaCl at 400 mmol/L has been shown to cause a -12.44mg/dL bias
- The following interpretive data is visible to practitioner: The following drugs will create a positive bias: Ceftriaxone, Deferoxamine mesylate.
Useful For
The filtration and resorption of plasma proteins in the formation of urine are important functions of the intact, healthy kidney. The presence of elevated concentrations of protein in urine (proteinuria) is a key finding in primary renal disease of glomerular, tubular, or mixed origin. Proteinuria is also seen in patients with systemic disorders that affect the kidneys such as diabetes mellitus, hypertension, vascular disease, neoplasia, drug toxicity, and certain infectious diseases. Proteinuria may also exist as either a benign or transient condition.