Test Code LH Luteinizing Hormone
Additional Codes
Cerner |
NextGen |
LH (Luteinizing Hormone) |
Luteinizing Hormone |
Alternate Name(s)
LH
Lutropin
Interstitial Cell Stimulating Hormone
ICSH
Useful For
LH is secreted by the anterior pituitary in response to hypothalamic gonadotrophin releasing hormone. During the menstrual cycle, follicle stimulating hormone (FSH) stimulates growth of the ovarian follicle which, when mature, ovulates in response to a surge of LH and, to a lesser extent, of FSH. Ovarian steroids are the primary negative feedback control for LH secretion. At menopause, reduced ovarian negative feedback results in elevated LH concentrations. LH concentrations also tend to be elevated in women of pre-menopausal age who experience ovarian failure, or whose ovaries failed to mature during puberty.
Methodology
Immunometric immunoassay, Chemiluminescent
Patient Preparation
None
Collection Instructions
Standard phlebotomy practices.
Specimen Requirements
Container |
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Stability |
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Rejection Criteria |
Gross Hemolysis Turbid Specimens |
Result Reporting and Reference Values
Reported in mIU/mL
|
Low |
High |
Postmenopausal Female |
13.1 |
86.5 |
Normal Female follicular phase |
2.58 |
12.1 |
Normal Female mid-cycle peak |
27.3 |
96.9 |
Normal Female luteal phase |
0.83 |
15.5 |
Reflex Testing
None
Limitations
- Ortho reports a bias with the following:
- Biotin can cause a negative bias
- Ortho reports no significant effect with the following:
- Bilirubin up to 40 mg/dL
- Hemoglobin up to 500 mg/dL