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Test Code HSCRP C-Reactive Protein, High Sensitivity, Serum

Additional Codes

Cerner

NextGen

C-Reactive Protein, High Sensitivity-Mayo

C-Reactive Protein, High Sensitivity-Mayo

C-Reactive Protein, Cardiac-Mayo

 

Reporting Name

C-Reactive Protein, High Sens, S

Useful For

Assessment of risk of developing myocardial infarction in patients presenting with acute coronary syndromes

 

Assessment of risk of developing cardiovascular disease or ischemic events in individuals who do not manifest disease at present

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Ordering Guidance


This assay should be used to assess risk of cardiovascular disease or events.

 

To monitor or assess other inflammatory disorders, order CRP / C-Reactive Protein (CRP), Serum.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  30 days

Reference Values

≥18 years: <2.0 mg/L

Reference values have not been established for patients who are younger than 18 years.

Day(s) Performed

Monday through Saturday

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86141

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HSCRP C-Reactive Protein, High Sens, S 30522-7

 

Result ID Test Result Name Result LOINC Value
HSCRP C-Reactive Protein, High Sens, S 30522-7

Clinical Information

C-reactive protein (CRP) is a biomarker of inflammation. Serum CRP concentrations increase rapidly and dramatically (100-fold or more) in response to tissue injury or inflammation. High-sensitivity CRP (hs-CRP) is more precise than standard CRP when measuring baseline (ie, normal) concentrations and enables a measure of chronic inflammation.

 

Atherosclerosis is an inflammatory disease and hs-CRP has been endorsed by multiple guidelines as a biomarker of atherosclerotic cardiovascular disease risk.(1-3)

 

A large prospective clinical trial demonstrated significantly less cardiovascular risk for patients with hs-CRP less than 2.0 mg/L.(1) More aggressive treatment strategies may be warranted in patients with hs-CRP of 2.0 mg/L or higher.

Interpretation

Values greater than 2.0 mg/L suggest an increased likelihood of developing cardiovascular disease or ischemic events.

Report Available

Same day/1 to 2 days

Specimen Retention Time

7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Method Name

Immunoturbidimetry

Forms

If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen.

Secondary ID

606909