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Test Code FPDPG Prostaglandin D2 (PGD2)


Specimen Required


Patient preparation: Patient should not be on aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen.

Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL

Collection Instructions:

1. Draw blood in a plain, red-top tube(s), serum-gel tube(s) is acceptable.

2. Centrifuge as soon as possible, aliquot 3 mL of serum into a plastic vial, and freeze immediately.

3. Send frozen.


Secondary ID

75900

Method Name

ELISA

Reporting Name

Prostaglandin D2 (PGD2)

Specimen Type

Serum

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen 60 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Specimens other than Serum or Plasma EDTA. Reject

Clinical Information

Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2, and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and Indomethacin.

Reference Values

35 - 115 pg/mL

No pediatric reference ranges available for this test.

Day(s) Performed

Monday through Friday

Report Available

5 to 9 days

Performing Laboratory

Inter Science Institute

Test Classification

This test was developed and its performance characteristics determined by Inter Science Institute. Values obtained with different methods, laboratories, or kits cannot be used interchangeably with the results on this report. The results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.

CPT Code Information

84150

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FPDPG Prostaglandin D2 (PGD2) Not Provided

 

Result ID Test Result Name Result LOINC Value
FPDPG Prostaglandin D2 (PGD2) 12839-7