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Test Code FNEU2 Neurotensin


Specimen Required


Patient preparation:

1. Fasting: 10 to 12 hours

2. Patient should not be on any antacid medication or medications that affect gastroentero-intestinal function, if possible, for at least 48 hours prior to collection.

Supplies: Z-Tube Preservative Inter Science Institute (T701)

Collection Container/Tube: Z-tube

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL plasma

Collection Instructions:

1. Draw 10 mL of blood directly into special Z-tube

2. As soon as possible, centrifuge and aliquot plasma into a plastic vial.

3. Freeze immediately after separation.

4. Ship frozen.


Secondary ID

75905

Method Name

Direct Radioimmunoassay

Reporting Name

Neurotensin

Specimen Type

Z-Tube Plasma

Specimen Minimum Volume

Plasma: 1 mL

Specimen Stability Information

Specimen Type Temperature Time
Z-Tube Plasma Frozen 180 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Specimens not collected in Z-Tube Reject

Clinical Information

Neurotensin is a 13 amino acid peptide produced primarily by endocrine cells of the ileal mucosa. Physiological actions of neurotensin include hypertension, vasodilation, hyperglycemia, and inhibition of gastric motility. Its C-terminus is similar to angiotensin I. It is a potent analgesic affecting hypothermia, muscle relaxation, and decreased motor activity. Pancreatic polypeptide secretion is strongly stimulated by neurotensin. Neurotensin appears to cause the release of luteinizing hormone-releasing hormone and corticotropin releasing hormone effecting the release of luteinizing hormone, follicle stimulating hormone, and ACTH but not thyroid-stimulating hormone or growth hormone. Neurotensin also stimulates pancreatic bicarbonate and intestinal secretion. Neurotensin levels are stimulated by food and bombesin. Elevated levels have been found in pancreatic endocrine tumors, oat cell, squamous cell, and adenocarcinomas. Elevated levels have been found to cause watery diarrhea.

Reference Values

50-100 pg/mL

Day(s) Performed

Monday, Thursday

Report Available

12 to 16 days

Performing Laboratory

Inter Science Institute

Test Classification

This test has not been cleared or approved by the US Food and Drug Administration. This test was developed and its performance characteristics determined by Inter Science Institute. Values obtained with different methods, laboratories, or kits cannot be used interchangeably with the results on this report. The results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.

CPT Code Information

83519

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FNEU2 Neurotensin 2655-9

 

Result ID Test Result Name Result LOINC Value
FNEU2 Neurotensin 2655-9