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Test Code FGHTP Ghrelin Total (Plasma)


Shipping Instructions


Ship Frozen



Specimen Required


Patient Preparation:

1. Patient should be fasting 10 to 12 hours prior to collection of specimen.

2. Patient should not be on any medications or supplements that may influence Cholecystokinin (CCK), Glucose, Growth Hormone, Insulin and/or Somatostatin levels, if possible, for at least 48 hours prior to specimen collection.

Supplies: Special ISI GI preservative plasma tube T125

Container/Tube:

Collection: Special ISI GI preservative plasma tube (T125).

Submission Container/Tube: Plastic vial

Specimen Volume: 3 to 5 mL

Collection Instructions:

1. Draw 10 mL of blood in special ISI GI preservative plasma tube (T125).

2. Centrifuge specimen in refrigerated centrifuge as soon as possible.

3. Send 3 to 5 mL plasma frozen.


Secondary ID

75898

Method Name

Direct RIA

Reporting Name

Ghrelin Total

Specimen Type

GI Plasma

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
GI Plasma Frozen 180 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Specimens other than collected in GI Tube supply (T125) Reject

Clinical Information

Ghrelin is a novel 28 amino acid peptide derived by post-translational processes from a preproghrelin consisting of 117 residues, secreted by the stomach with specific receptors in the brain involved in appetite regulation. It conveys information to the brain thereby increasing appetite, food intake and body weight and influences the release of growth hormone. Ghrelin is a growth hormone-releasing peptide which acts as an endogenous ligand of the growth hormone secretagogue receptors (GHS-Rs). Ghrelin levels are inversely correlated with body weight and are higher during weight loss.

Reference Values

Normal weight/control subjects: 520-700 pg/mL

 

Obese subjects prior to diet: 340-450 pg/mL

8:00 am-12:00 pm: Up to 420 pg/mL

6:00pm: Up to 480 pg/mL

 

Obese subjects post induced

Weight loss: 450-600 pg/mL

8:00 am-12:00 pm: Up to 575 pg/mL

6:00 pm: Up to 600 pg/mL

 

Obese subjects post gastric-bypass surgery: Up to 120 pg/mL

Day(s) Performed

Monday through Friday

Report Available

5 to 9 days

Performing Laboratory

Inter Science Institute

Test Classification

This test was developed and its performance characteristics determined by Inter Science Institute. Values obtained with different methods, laboratories, or kits cannot be used interchangeably with the results on this report. The results cannot be interpreted as absolute evidence of the presences or absence of malignant disease.

CPT Code Information

83519

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FGHTP Ghrelin Total 76474-6

 

Result ID Test Result Name Result LOINC Value
FGHTP Ghrelin Total 76474-6