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Test Code FCLMS Clonazepam and Metabolite, Serum


Specimen Required


***Must submit one specimen per order. Specimens cannot be shared between multiple orders.***

Specimen Type: Serum

Collection Container/Tube: Red top

Submission Container/Tube: Plastic, preservative-free vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and send 1 mL of serum refrigerated in a plastic vial.


Secondary ID

75524

Method Name

High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Clonazepam and Metabolite, S

Specimen Type

Serum Red

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 14 days
  Frozen  30 days

Reject Due To

Received room temperature Reject
Polymer gel separation tube (SST or PST) Reject

Reference Values

Reporting limit(s) determined each analysis.

Clonazepam: None detected

7-Amino Clonazepam: None detected

Interpretation

Clonazepam:

Dose and route: average concentration and time

-Single 2 mg IM: peak 11 ng/mL at 3.1 hr

-Single 2 mg oral: peak 15 ng/mL at 1.7 hr

-Daily 6 mg oral: 29-75 ng/mL

-Half-life: approximately 19-60 hr

 

7-Amino Clonazepam:

Clonazepam dose and route: average 7-amino clonazepam plasma concentration

-Daily 6 mg oral: 23-137 ng/mL

Day(s) Performed

Monday through Sunday

Report Available

7 to 11 days

Performing Laboratory

NMS Labs

Test Classification

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FCLMS Clonazepam and Metabolite, S Not Provided

 

Result ID Test Result Name Result LOINC Value
Z6336 Clonazepam 3494-2
Z6337 7-Amino Clonazepam 28059-4