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Test Code CRP C-Reactive Protein Quantitative

Additional Codes

Cerner

NextGen

C-Reactive Protein Quant

C-Reactive Protein Quantitative

CRP Quant

 

Alternate Name(s)

CRP

C-Reactive Protein

Useful For

CRP is synthesized by the liver and is one of the acute phase proteins. In the acute phase response, increased concentrations of several plasma proteins, including CRP, are observed. CRP concentration measurements are useful in the detection and evaluation of inflammatory disorders, tissue injury, and infections.

Methodology

Fixed-point immuno-rate

Patient Preparation

None

Collection Instructions

Standard phlebotomy practices.

Specimen Requirements

Container

Specimen Type

Tube

Lithium Heparin Plasma

PST

 or 

Serum

 or 

SST

 or 

 

Stability

Storage

Temperature

Stability

Room Temperature

18-28°C

≤ 4 hours

Refrigerated

 2-8°C

≤ 3 days

If separated within 4 hours

Frozen

≤-18 °C

≤ 6 months

If separated within 4 hours

Rejection Criteria

Gross Hemolysis

Result Reporting and Reference Values

Reported as mg/dL.

Age

Normal value

0-150Y

<1.0

Reflex Testing

None

Limitations

  • Ortho reports a bias with the following:
    • Ampicillin at 200 mg/dL has a negative bias
    • Gentisic Acid at 5 mg/dL has a negative bias
  • Ortho reports no significant effect with the following:
    • Hemoglobin up to 268 mg/dL
    • Bilirubin up to 25 mg/dL
    • Lipemia up to 800 mg/dL
  • The following interpretive data is visible to the practitioner:
    • Total protein below 4.9 g/dL creates a positive bias of about 15%, total protein above 9.5 g/dL creates a negative bias of about 15%.