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Test Code CLU24H Chloride Urine 24 Hour

Additional Codes

Cerner

NextGen

Chloride Urine 24 Hr

Chloride Urine 24 Hr

Useful For

Chloride is the major anion in the extracellular water space; its physiological significance is in maintaining proper body water distribution, osmotic pressure, and normal anion-cation balance in the extracellular fluid compartment. Chloride is increased in dehydration, in renal tubular acidosis (hyperchloremia metabolic acidosis), and in excessive infusion of isotonic saline. Chloride is decreased in overhydration, chronic respiratory acidosis, salt-losing nephritis, metabolic alkalosis, and congestive heart failure.

Methodology

Potentiometric

Patient Preparation

None

Collection Instructions

Catheterized specimens collected according to clinical policies and procedures

24 Hour Urine Collection Instructions

Specimen Requirements

Container

Stability

Storage

Temperature

Stability

Room Temperature

18-28°C

≤ 24 hours

 

Refrigerated

 2-8°C

≤ 7 days

 

Frozen

≤-18 °C

6 months

 

Rejection Criteria

Not Defined

Result Reporting and Reference Values

110-250 mmol/24 hours

Reflex Testing

None

Limitations

  • Ortho reports a bias with the following:
    • 5-aminosalicylic acid at 4 mg/dl may cause a negative bias
    • Glutathione at 1 mg/dL may cause a negative bias
    • Naproxen at 504.5 mg/dL may cause a positive bias
    • Terazosin at 3.03 may cause a negative bias
    • Lipemia at 600 mg/dL may cause a positive bias
    • Bromide and Iodide may cause a positive bias
  • Ortho reports no significant effect with the following: 
    • Bilirubin up to 40 mg/dL
    • Hemoglobin up to 1000 mg/dL
  • The following interpretive data is visible to the practitioner:
    • Bromide and iodide from therapeutic drugs and ointments may cause a positive bias of 5-6 mmol/L