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Test Code CEA Carcinoembryonic Antigen (CEA)

Additional Codes

Cerner

NextGen

Carcinoembryonic Antigen (CEA)

Carcinoembryonic Antigen (CEA)

Alternate Name(s)

Embryonic Carcinoma Antigen

Methodology

(Ortho) Chemiluminescence-Immunometric

Patient Preparation

None

Collection Instructions

Standard phlebotomy practices.

Centrifuge specimens and remove serum from cells within 2 hours of collection.

Specimen Requirements

Container

Specimen Type

Tube

Serum

 or 

SST

 or  or 

 

Stability

Storage

Temperature

Stability

Room Temperature

18-28°C

≤ 2 hours

Refrigerated

 2-8°C

≤ 1 week

Frozen

≤ -20 °C

≤ 1 month  

Avoid repeated freeze- thaw cycles

Rejection Criteria

Lipemic or Turbid Specimens

Result Reporting and Reference Values

Reported in ng/mL

Category

Low

High

Nonsmokers

0

3.0

Smokers

0

5.0

Reflex Testing

None

Limitations

  • Values obtained with different assay methods may be different and cannot be used interchangeably.
  • Test results cannot be interpreted as absolute evidence for the presence or absence of malignant disease.

Useful For

To aid in the prognosis and management of cancer patients in whom changing concentrations of CEA are observed.

Increased levels may be found in patients with primary colorectal cancer or other malignancies including medullary thyroid carcinoma and breast, gastrointestinal tract, liver, lung, ovarian, pancreatic, and prostatic cancers.

Serial monitoring of CEA should begin prior to therapy to verify post therapy decrease in concentration and to establish a baseline for evaluating possible recurrence. Levels generally return to normal within 1 to 4 months after removal of cancerous tissue.