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Test Code BUPU Buprenorphine Drug Screen Urine

Additional Codes

Cerner

NextGen

Tox U Buprenorphine Drug Screen

Tox U Buprenorphine Drug Screen

Buprenorphine Drug Screen

 

Alternate Name(s)

Subutex

Suboxone

Buprenex

Methodology

Lateral flow chromatographic immunoassay

Patient Preparation

None

Collection Instructions

Catheterized specimens collected according to clinical policies and procedures

Radom clean catch instructions: Random Urine Collection Instructions

Specimen Requirements

Container
  • Sterile/clean plastic urine container

 or  or 

  • Non-preservative urine tube (BD Vacutainer® Ref #364980)

Stability

Storage

Temperature

Stability

Room Temperature

18-28°C

Assay within 3 hours of collection or store refrigerated.

Refrigerated

 2-8°C

≤ 96 hours

Rejection Criteria

Not Defined

Result Reporting and Reference Values

Negative cut-off is 10 ng/mL

Reflex Testing

None

Limitations

  • The TOX/SeeTM Drug screen test provides only a qualitative, preliminary analytical result. A secondary analytical method should be used to obtain a confirmed result. Gas chromatography/ Mass spectrometry (GC/MS) or Liquid Chromatography/Mass Spectrometry (LC/MS) is acceptable for confirmation testing.
  • There is a possibility that technical or procedural errors, as well as other interfering substances in the urine specimen may cause erroneous results.
  • Adulterants, such as bleach and/or alum, in urine specimens may produce erroneous results regardless of the analytical method used. If adulteration is suspected, the test should be repeated with another urine specimen.
  • A positive result does not indicate level or intoxication, administration route or concentration in urine.
  • A negative result may not necessarily indicate drug-free urine. Negative results can be obtained when drug is present but below the cut-off level of the test.
  • The test does not distinguish between drugs of abuse and certain medications.

Useful For

Urine based test for detection of Buprenorphine. Buprenorphine is a potent analgesic often used in the treatment of opioid addiction. Therapeutically, Buprenorphine is used as a substitution treatment for opioid addicts. In substitution therapy, Buprenorphine is as effective as Methadone but demonstrates a lower level of physical dependence. The plasma half-life of buprenorphine is 2-4 hours. Complete elimination of a single dose can take as long as 6 days. The detection window for the parent drug is thought to be approximately 3 days. Substantial abuse of Buprenorphine has been reported and has been diverted from legitimate channels through theft, doctor shopping, and fraudulent prescriptions.